About Us
This work is one of the major tasks of the Bio/Chem-informatics in Personalized Medicine (BCIPM) Project, which is supported by National Natural Science Foundation of China.
The major tasks of the project are:
Predicting the serious adverse drug reaction (SADR) of a compound through pattern recognition based on its Chemical-Protein Interactome profile;
Identifying candidate genes for SADR, exploring brand new therapeutic targets and new indication of the drugs through constructing and mining a comprehensive
Chemical-Protein Interactome (CPI);
Predicting the population susceptible to SADR;
Bibliomics database construction and network modeling of genes related to SADR (SADR Gengle™).
Principle Investigator: Lun Yang Ph. D
Algorithm design & CGI programming: Lun Yang Ph. D, Module of Bioinformatics, Bio-X Center, Fudan University/Chinese Academy of Sciences/Shanghai Jiao Tong University
How to cite?
Lun Yang, Langlai Xu, Lin He. A CitationRank Algorithm Inheriting Google Technology Designed to Highlight Genes Responsible for Serious Adverse Drug Reaction. Bioinformatics. 2009;25(17):2244-50. [pdf] [html] doi:10.1093/bioinformatics/btp369
