SADR Gengle™ - a Database Inheriting Google® Technology in Presenting Genes Responsible for Serious Adverse Drug Reactions

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QT Prolongation



Pathway Foreground Gene Count & Ratio Background Gene Count & Ratio p-value q-value
Prostate cancer 35 / 7.92% 90 / 1.12% 5.52E-17 7.45E-15
Small cell lung cancer 29 / 6.56% 85 / 1.06% 4.29E-13 2.90E-11
Insulin signaling pathway 34 / 7.69% 132 / 1.64% 3.30E-12 1.48E-10
Cell cycle 31 / 7.01% 115 / 1.43% 1.15E-11 3.89E-10
Chronic myeloid leukemia 24 / 5.43% 72 / 0.90% 7.05E-11 1.90E-09
Calcium signaling pathway 36 / 8.14% 171 / 2.13% 1.09E-10 2.45E-09
Jak-STAT signaling pathway 21 / 4.75% 56 / 0.70% 1.92E-10 3.69E-09
Toll-like receptor signaling pathway 27 / 6.11% 103 / 1.28% 4.33E-10 7.30E-09
Adipocytokine signaling pathway 22 / 4.98% 68 / 0.85% 7.09E-10 1.06E-08
Glioma 21 / 4.75% 64 / 0.80% 1.41E-09 1.90E-08
Apoptosis 24 / 5.43% 88 / 1.10% 2.12E-09 2.61E-08
Acute myeloid leukemia 19 / 4.30% 54 / 0.67% 3.38E-09 3.80E-08
Pancreatic cancer 21 / 4.75% 69 / 0.86% 4.32E-09 4.49E-08
MAPK signaling pathway 43 / 9.73% 277 / 3.45% 7.35E-09 7.08E-08
T cell receptor signaling pathway 23 / 5.20% 89 / 1.11% 1.10E-08 9.89E-08
Long-term potentiation 20 / 4.52% 69 / 0.86% 2.02E-08 1.68E-07
mTOR signaling pathway 17 / 3.85% 48 / 0.60% 2.12E-08 1.68E-07
GnRH signaling pathway 23 / 5.20% 94 / 1.17% 2.63E-08 1.97E-07
Protein kinases 57 / 12.90% 463 / 5.76% 4.83E-08 3.43E-07
Bladder cancer 15 / 3.39% 40 / 0.50% 7.87E-08 5.31E-07
Progesterone-mediated oocyte maturation 23 / 5.20% 103 / 1.28% 1.11E-07 7.16E-07
ErbB signaling pathway 19 / 4.30% 84 / 1.05% 1.21E-06 7.44E-06
Cytochrome P450 15 / 3.39% 52 / 0.65% 1.28E-06 7.53E-06
B cell receptor signaling pathway 17 / 3.85% 69 / 0.86% 1.63E-06 9.17E-06
Metabolism of xenobiotics by cytochrome P450 17 / 3.85% 70 / 0.87% 1.93E-06 1.04E-05
Melanoma 17 / 3.85% 71 / 0.88% 2.28E-06 1.18E-05
Gap junction 20 / 4.52% 98 / 1.22% 2.55E-06 1.27E-05
p53 signaling pathway 16 / 3.62% 65 / 0.81% 3.34E-06 1.61E-05
Renin - angiotensin system 9 / 2.04% 17 / 0.21% 3.72E-06 1.73E-05
Focal adhesion 29 / 6.56% 199 / 2.48% 6.88E-06 3.10E-05
Melanogenesis 19 / 4.30% 101 / 1.26% 1.26E-05 5.50E-05
Type II diabetes mellitus 12 / 2.71% 41 / 0.51% 1.32E-05 5.57E-05
Endometrial cancer 13 / 2.94% 51 / 0.63% 2.03E-05 8.22E-05
Colorectal cancer 17 / 3.85% 86 / 1.07% 2.07E-05 8.22E-05
Non-small cell lung cancer 13 / 2.94% 53 / 0.66% 2.87E-05 1.11E-04
Linoleic acid metabolism 10 / 2.26% 31 / 0.39% 3.50E-05 1.31E-04
Olfactory transduction 9 / 2.04% 28 / 0.35% 8.86E-05 3.23E-04
Wnt signaling pathway 21 / 4.75% 149 / 1.86% 1.95E-04 6.92E-04
Long-term depression 14 / 3.17% 76 / 0.95% 2.12E-04 7.33E-04
Renal cell carcinoma 13 / 2.94% 67 / 0.83% 2.27E-04 7.66E-04
Adherens junction 13 / 2.94% 72 / 0.90% 4.19E-04 1.38E-03
Huntington's disease 8 / 1.81% 29 / 0.36% 5.20E-04 1.67E-03
Chaperones and folding catalysts 19 / 4.30% 142 / 1.77% 6.91E-04 2.17E-03
Arachidonic acid metabolism 10 / 2.26% 54 / 0.67% 1.61E-03 4.95E-03
Natural killer cell mediated cytotoxicity 18 / 4.07% 142 / 1.77% 1.65E-03 4.95E-03
VEGF signaling pathway 11 / 2.49% 67 / 0.83% 2.25E-03 6.61E-03
Leukocyte transendothelial migration 15 / 3.39% 113 / 1.41% 2.64E-03 7.58E-03
Neuroactive ligand-receptor interaction 29 / 6.56% 293 / 3.65% 2.75E-03 7.75E-03
Transcription factors 75 / 16.97% 986 / 12.28% 3.18E-03 8.76E-03
Epithelial cell signaling in Helicobacter pylori infection 10 / 2.26% 65 / 0.81% 5.30E-03 1.43E-02
Pores ion channels 4 / 0.90% 12 / 0.15% 8.05E-03 2.13E-02
Thyroid Cancer 6 / 1.36% 29 / 0.36% 8.70E-03 2.26E-02
Caffeine metabolism 3 / 0.68% 7 / 0.09% 1.28E-02 3.27E-02
Monoterpenoid biosynthesis 2 / 0.45% 2 / 0.02% 1.52E-02 3.80E-02
Regulation of actin cytoskeleton 20 / 4.52% 213 / 2.65% 1.92E-02 4.72E-02
Complement and coagulation cascades 9 / 2.04% 69 / 0.86% 1.97E-02 4.75E-02

Query Genes


Prostate cancer PDGFRB;  FRAP1;  CCND1;  E2F2;  BAD;  PIK3R1;  PIK3CA;  PDGFRA;  HSP90AA1;  SRD5A2;  HSP90AB1;  RELA;  PTEN;  IKBKB;  GRB2;  RB1;  EP300;  AR;  IKBKG;  GSK3B;  MDM2;  RAF1;  E2F1;  SRD5A1;  NFKB1;  NFKB2;  NFKBIA;  CDKN1B;  CDKN1A;  MAPK3;  KLK3;  KRAS;  CREB1;  CREBBP;  ERBB2;  
Small cell lung cancer CCND1;  PIAS3;  PIK3R1;  XIAP;  BIRC3;  PIK3CA;  E2F2;  PTK2;  PTEN;  IKBKB;  RB1;  NOS1;  IKBKG;  PIAS2;  PIAS1;  MYC;  E2F1;  NFKB1;  NFKB2;  NFKBIA;  ITGB1;  FN1;  SKP2;  ITGAV;  TRAF6;  RELA;  TRAF1;  TRAF2;  TRAF3;  
Insulin signaling pathway FRAP1;  BAD;  PIK3R1;  PIK3CA;  SREBF1;  FASN;  PPP1CA;  RHEB;  PRKACG;  IKBKB;  GRB2;  PRKAB1;  PRKAB2;  PRKACA;  PRKACB;  PRKAA1;  PRKAA2;  SOCS1;  LIPE;  IRS1;  GSK3B;  RAF1;  MAPK3;  FLOT2;  PRKAR2B;  PRKAR2A;  PRKAR1A;  PRKAG1;  PRKAG2;  MAPK8;  CALM3;  KRAS;  CALM1;  RPS6KB1;  
Cell cycle YWHAB;  CCND1;  E2F2;  SMAD4;  HDAC2;  HDAC1;  YWHAQ;  CCND3;  CHEK1;  RB1;  EP300;  CDC2;  YWHAZ;  YWHAE;  YWHAH;  YWHAG;  PRKDC;  SFN;  CDC25A;  ATR;  GSK3B;  MDM2;  E2F1;  MCM5;  CDKN1B;  CDKN1A;  MCM3;  SKP2;  CDKN2A;  RBL1;  CREBBP;  
Chronic myeloid leukemia CCND1;  E2F2;  SMAD4;  PIK3R1;  PIK3CA;  HDAC2;  HDAC1;  IKBKB;  GRB2;  RB1;  BAD;  IKBKG;  MDM2;  RAF1;  MYC;  E2F1;  NFKB1;  NFKB2;  NFKBIA;  CDKN1A;  MAPK3;  CDKN2A;  KRAS;  RELA;  
Calcium signaling pathway PDGFRB;  ADRB1;  ADRB3;  ADRB2;  BDKRB2;  PDGFRA;  ADORA2A;  ITPR3;  DRD5;  PRKACG;  PLN;  PRKACA;  PRKACB;  CAMK2G;  LHCGR;  AGTR1;  CAMK2A;  NOS1;  CACNA1C;  CACNA1B;  GNA15;  CACNA1D;  ADRA1A;  ITPR1;  PTK2B;  ATP2A2;  RYR2;  ITPKA;  HTR2C;  PPID;  SLC8A1;  ADRA1B;  CALM3;  CALM1;  ERBB2;  F2R;  
Jak-STAT signaling pathway PIAS3;  JAK2;  PIK3R1;  STAT6;  CCND3;  GRB2;  STAT4;  STAT5A;  STAT5B;  PIAS2;  STAT1;  STAT2;  MYC;  JAK1;  EP300;  PIK3CA;  PIAS1;  IRF9;  SOCS1;  CCND1;  CREBBP;  
Toll-like receptor signaling pathway IL12B;  MAP3K8;  PIK3R1;  PIK3CA;  IRAK1;  TLR2;  IFNAR1;  IFNAR2;  IKBKE;  RIPK1;  IKBKG;  IRF3;  CD40;  TICAM1;  MAP3K7;  MAPK14;  NFKB1;  NFKB2;  NFKBIA;  MAPK3;  IKBKB;  CASP8;  MAPK8;  TRAF6;  FOS;  RELA;  TRAF3;  
Adipocytokine signaling pathway FRAP1;  JAK1;  JAK2;  IKBKB;  PRKAB1;  PRKAB2;  PRKAA1;  PRKAA2;  IKBKG;  IRS1;  LEPR;  ADIPOQ;  NFKBIE;  NFKB1;  NFKB2;  NFKBIA;  STK11;  MAPK8;  PRKAG1;  PRKAG2;  RELA;  TRAF2;  
Glioma PDGFRB;  FRAP1;  CDKN1A;  MAPK3;  GRB2;  CCND1;  PIK3R1;  CDKN2A;  PTEN;  PIK3CA;  PDGFRA;  CAMK2G;  RB1;  MDM2;  CALM3;  RAF1;  E2F2;  E2F1;  KRAS;  CALM1;  CAMK2A;  
Apoptosis BAD;  PIK3R1;  XIAP;  BIRC3;  PIK3CA;  IRAK1;  NGF;  PRKACG;  IKBKB;  PRKACA;  PRKACB;  RIPK1;  IKBKG;  BAX;  NFKB1;  NFKB2;  NFKBIA;  CASP8;  PRKAR2B;  PRKAR2A;  PRKAR1A;  FAS;  RELA;  TRAF2;  
Acute myeloid leukemia NFKB1;  IKBKG;  FRAP1;  MAPK3;  IKBKB;  KIT;  BAD;  PIK3R1;  PIK3CA;  SPI1;  CCND1;  CEBPA;  RAF1;  MYC;  GRB2;  KRAS;  RELA;  RPS6KB1;  NFKB2;  
Pancreatic cancer IKBKG;  CCND1;  MAPK3;  IKBKB;  MAPK8;  BAD;  BRCA2;  PIK3R1;  CDKN2A;  ERBB2;  PIK3CA;  RB1;  VEGFC;  RAF1;  E2F2;  SMAD4;  E2F1;  KRAS;  RELA;  NFKB1;  NFKB2;  
MAPK signaling pathway MAP3K3;  MAP3K8;  STMN1;  PDGFRA;  MEF2C;  CACNA1D;  HSPA1L;  HSPA1A;  NGF;  PRKACG;  IKBKB;  TRAF6;  PRKACA;  PRKACB;  FAS;  ARRB2;  ARRB1;  CACNA1C;  IKBKG;  CACNA1B;  GNA12;  GSTA1;  MAP3K7;  RAF1;  PPP5C;  MYC;  MAPK14;  HSPA8;  NFKB1;  NFKB2;  CACNB3;  CACNB4;  MAPK3;  CACNA2D1;  CACNB2;  MAPK8;  GRB2;  RPS6KA1;  RPS6KA2;  RPS6KA3;  KRAS;  FOS;  TRAF2;  
T cell receptor signaling pathway MAP3K8;  PIK3R1;  PIK3CA;  CD40LG;  IKBKB;  GRB2;  MALT1;  IL2;  PTPN6;  ZAP70;  IKBKG;  LCK;  NFATC1;  NFATC2;  NFKBIE;  CARD11;  NFKB1;  NFKB2;  NFKBIA;  PAK6;  KRAS;  BCL10;  FOS;  
Long-term potentiation CAMK2A;  CACNA1C;  PRKACG;  MAPK3;  ITPR3;  RAPGEF3;  PRKACA;  PRKACB;  RPS6KA2;  CALM3;  CAMK2G;  RPS6KA1;  ITPR1;  RPS6KA3;  RAF1;  PPP1CA;  KRAS;  CALM1;  CREBBP;  EP300;  
mTOR signaling pathway LYK5;  FRAP1;  CAB39;  MAPK3;  HIF1A;  PIK3R1;  DDIT4;  STK11;  PIK3CA;  PRKAA2;  RPS6KA1;  RPS6KA2;  RPS6KA3;  PRKAA1;  VEGFC;  RHEB;  RPS6KB1;  
GnRH signaling pathway MAP3K3;  ITPR3;  MMP14;  PLD1;  PLD2;  PRKACG;  GRB2;  PRKACA;  PRKACB;  CAMK2G;  CAMK2A;  CACNA1C;  CACNA1D;  ITPR1;  RAF1;  PTK2B;  MAPK14;  SRC;  MAPK3;  MAPK8;  CALM3;  KRAS;  CALM1;  
Protein kinases PDGFRB;  FRAP1;  JAK1;  MAP3K8;  ADRBK1;  CDC2;  JAK2;  PDGFRA;  PTK2;  IRAK1;  CHEK1;  PRKACG;  IKBKB;  PRKCE;  PRKACA;  PRKACB;  PRKAA1;  PRKAA2;  CAMK2G;  TRIM24;  CSNK2A1;  GRK5;  ZAP70;  RIPK1;  CSNK2B;  MAP3K3;  IKBKG;  KIT;  ATR;  GSK3B;  ERBB2;  LCK;  MAP3K7;  RAF1;  PTK2B;  MAPK3;  SRC;  GSK3A;  IKBKE;  CAMK1;  CDK9;  STK11;  PRKG1;  MAPK14;  CDK5;  AURKA;  MAPK8;  PRKDC;  EIF2AK2;  PAK6;  CAMK2A;  RPS6KA1;  RPS6KA2;  RPS6KA3;  EEF2K;  RPS6KB1;  CSNK2A2;  
Bladder cancer CCND1;  CDKN1A;  MAPK3;  MMP9;  CDKN2A;  CDH1;  MDM2;  RB1;  VEGFC;  RAF1;  E2F2;  MYC;  E2F1;  KRAS;  ERBB2;  
Progesterone-mediated oocyte maturation GNAI1;  CDC2;  GNAI3;  PIK3CA;  HSP90AA1;  HSP90AB1;  PRKACG;  PRKACA;  PRKACB;  GNAI2;  PIK3R1;  CDC25A;  PDE4D;  PDE3B;  RAF1;  MAPK3;  MAPK14;  MAPK8;  PGR;  RPS6KA1;  RPS6KA2;  RPS6KA3;  KRAS;  
ErbB signaling pathway FRAP1;  CDKN1A;  MAPK3;  GRB2;  MAPK8;  BAD;  PIK3R1;  GSK3B;  PAK6;  PIK3CA;  CAMK2G;  ERBB2;  MYC;  RAF1;  PTK2;  KRAS;  SRC;  RPS6KB1;  CAMK2A;  
Cytochrome P450 CYP3A7;  CYP2E1;  CYP19A1;  CYP1B1;  CYP2B6;  CYP2C19;  CYP2C9;  CYP2C8;  CYP1A2;  CYP2A6;  CYP3A4;  CYP3A43;  CYP2J2;  CYP2C18;  CYP2D6;  
B cell receptor signaling pathway IKBKG;  IKBKB;  NFATC1;  MALT1;  PIK3R1;  GSK3B;  PIK3CA;  CARD11;  NFKBIE;  KRAS;  NFATC2;  BCL10;  NFKBIA;  FOS;  NFKB1;  NFKB2;  PTPN6;  
Metabolism of xenobiotics by cytochrome P450 CYP3A7;  CYP1A2;  EPHX1;  CYP2B6;  GSTA1;  CYP2C19;  CYP2C9;  CYP2C8;  UGT2B7;  CYP3A43;  CYP3A4;  CYP1B1;  UGT2B15;  CYP2C18;  UGT2B17;  UGT1A6;  CYP2E1;  
Melanoma PDGFRB;  CCND1;  CDKN1A;  MAPK3;  BAD;  PIK3R1;  CDKN2A;  PTEN;  PIK3CA;  PDGFRA;  CDH1;  RB1;  MDM2;  RAF1;  E2F2;  E2F1;  KRAS;  
Gap junction PDGFRB;  ADRB1;  PRKG1;  MAPK3;  ITPR3;  DRD2;  GNAI3;  CDC2;  PRKACA;  PRKACB;  PDGFRA;  GNAI1;  ITPR1;  PRKACG;  RAF1;  GNAI2;  GRB2;  KRAS;  SRC;  HTR2C;  
p53 signaling pathway PTEN;  CDKN1A;  CCND1;  SFN;  CASP8;  BAX;  CCND3;  CDC2;  TP73;  CDKN2A;  MDM2;  BBC3;  CHEK1;  FAS;  RCHY1;  ATR;  
Renin - angiotensin system ACE;  CMA1;  ENPEP;  AGT;  ACE2;  AGTR2;  AGTR1;  REN;  CTSG;  
Focal adhesion PDGFRB;  CCND1;  BAD;  PIK3R1;  XIAP;  BIRC3;  PIK3CA;  PDGFRA;  PPP1CA;  PTK2;  THBS2;  CAV1;  GRB2;  ITGB3;  CAV3;  CCND3;  GSK3B;  PTEN;  RAF1;  SRC;  ITGB1;  MAPK3;  FN1;  MAPK8;  PAK6;  ITGAV;  VEGFC;  VASP;  ERBB2;  
Melanogenesis GNAI3;  MAPK3;  KIT;  GNAI1;  GNAI2;  PRKACA;  PRKACB;  GSK3B;  GNAO1;  CAMK2A;  CAMK2G;  KRAS;  CALM3;  RAF1;  PRKACG;  CREB1;  CALM1;  CREBBP;  EP300;  
Type II diabetes mellitus CACNA1C;  CACNA1B;  FRAP1;  CACNA1D;  MAPK3;  IKBKB;  MAPK8;  ADIPOQ;  PIK3R1;  IRS1;  PIK3CA;  SOCS1;  
Endometrial cancer CCND1;  MAPK3;  GRB2;  BAD;  PIK3R1;  CDH1;  PTEN;  PIK3CA;  RAF1;  MYC;  KRAS;  GSK3B;  ERBB2;  
Colorectal cancer PDGFRB;  CCND1;  MAPK3;  BAX;  MAPK8;  BAD;  PIK3R1;  GSK3B;  PIK3CA;  PDGFRA;  KRAS;  MYC;  RAF1;  SMAD4;  GRB2;  FOS;  BIRC5;  
Non-small cell lung cancer CCND1;  MAPK3;  GRB2;  BAD;  PIK3R1;  CDKN2A;  PIK3CA;  RB1;  RAF1;  E2F2;  E2F1;  KRAS;  ERBB2;  
Linoleic acid metabolism CYP3A7;  CYP1A2;  CYP2C19;  CYP2C9;  CYP2C8;  CYP3A43;  CYP3A4;  CYP2J2;  CYP2C18;  CYP2E1;  
Olfactory transduction PRKG1;  PRKACG;  PRKACA;  PRKACB;  PDC;  CAMK2G;  CALM3;  CALM1;  CAMK2A;  
Wnt signaling pathway CAMK2A;  CCND1;  PRKACB;  BTRC;  CCND3;  MAPK8;  SMAD4;  PRKACA;  CSNK2A1;  GSK3B;  CSNK2B;  FOSL1;  CAMK2G;  MAP3K7;  EP300;  NFATC2;  MYC;  PRKACG;  CREBBP;  CSNK2A2;  NFATC1;  
Long-term depression GNA12;  MAPK3;  ITPR3;  GNAZ;  GNAI1;  GNAI2;  GNAI3;  GNAO1;  ITPR1;  PRKG1;  KRAS;  GNA13;  RAF1;  NOS1;  
Renal cell carcinoma MAPK3;  EPAS1;  PIK3R1;  PAK6;  PIK3CA;  GRB2;  ARNT;  HIF1A;  RAF1;  VEGFC;  KRAS;  CREBBP;  EP300;  
Adherens junction MAPK3;  SMAD4;  CDH1;  CSNK2B;  CSNK2A1;  EP300;  PTPN6;  SRC;  MAP3K7;  CREBBP;  ERBB2;  CSNK2A2;  WASL;  
Huntington's disease CASP8;  NCOR1;  CBS;  GRB2;  CALM3;  EP300;  CALM1;  CREBBP;  
Chaperones and folding catalysts FKBP4;  FKBP5;  HSPA1L;  STIP1;  TXN;  CDC37;  BAG1;  FKBP8;  HSPA4;  DNAJA3;  HSP90AA1;  HSPBP1;  DNAJB1;  HSP90AB1;  STUB1;  DNAJC15;  HSPA8;  HSPA1A;  PPID;  
Arachidonic acid metabolism EPHX2;  CYP2B6;  CYP2C19;  CYP2C9;  CYP2C8;  ALOX12;  PTGES;  CYP2J2;  CYP2C18;  CYP2E1;  
Natural killer cell mediated cytotoxicity IFNAR2;  ITGB2;  PIK3R1;  MAPK3;  IFNAR1;  IFNGR2;  NFATC1;  IFNGR1;  PIK3CA;  LCK;  GRB2;  FAS;  RAF1;  NFATC2;  PTK2B;  ZAP70;  KRAS;  PTPN6;  
VEGF signaling pathway MAPK14;  NFATC1;  BAD;  PIK3R1;  PIK3CA;  KRAS;  RAF1;  NFATC2;  PTK2;  MAPK3;  SRC;  
Leukocyte transendothelial migration MMP9;  ITGB2;  ITGB1;  MAPK14;  RAPGEF3;  GNAI3;  GNAI2;  PIK3R1;  PIK3CA;  VCAM1;  GNAI1;  VASP;  PTK2B;  PTK2;  NCF1;  
Neuroactive ligand-receptor interaction ADRA2B;  ADRA2A;  ADRB1;  ADRA2C;  ADRB3;  ADRB2;  BDKRB2;  AVPR2;  ADORA2A;  EDN1;  PRSS2;  DRD3;  DRD5;  DRD2;  GABRG2;  LHCGR;  OPRD1;  AGTR1;  AGTR2;  ADRA1B;  GRM4;  LEPR;  ADRA1A;  HTR2C;  TAC1;  FSHR;  FPR2;  CTSG;  F2R;  
Transcription factors NR2F1;  TP73;  NR3C2;  BCL3;  IRF9;  KLF11;  NFKBIE;  MEF2C;  SREBF1;  IRF1;  E2F2;  FOXA1;  HSF1;  NFYA;  NFYB;  SP2;  KLF4;  ESR2;  CEBPA;  ETV5;  NFATC1;  POU2F1;  WT1;  MZF1;  SP1;  KLF8;  SPI1;  RB1;  ARNT;  EPAS1;  EP300;  AR;  ETS1;  ETV1;  REL;  ETV4;  GATA1;  AHR;  IRF3;  NCOA2;  CEBPB;  ATF1;  NCOA3;  FOSL1;  TFAP2B;  TFAP2A;  SP4;  SP3;  SRY;  CREB1;  E2F1;  NFKB2;  FOXO3;  NFKB1;  RELB;  NFKBIA;  GABPA;  RELA;  STAT6;  IRF8;  ELF1;  STAT4;  STAT5A;  STAT5B;  PGR;  STAT1;  STAT2;  MYC;  HIF1A;  RBL1;  NCOA1;  FOS;  YY1;  CREBBP;  NFATC2;  
Epithelial cell signaling in Helicobacter pylori infection IKBKG;  MAPK14;  IKBKB;  MAPK8;  IL8RA;  SRC;  RELA;  NFKB1;  NFKB2;  NFKBIA;  
Pores ion channels HSPA8;  HSPA1L;  HSPA1A;  HSPA4;  
Thyroid Cancer CCND1;  MAPK3;  CDH1;  KRAS;  MYC;  NCOA4;  
Caffeine metabolism NAT1;  CYP1A2;  CYP2A6;  
Monoterpenoid biosynthesis CYP2C9;  CYP2C19;  
Regulation of actin cytoskeleton PDGFRB;  ITGB2;  ITGB1;  MAPK3;  FN1;  ITGAV;  BDKRB2;  ITGB3;  GNA13;  PIK3R1;  PAK6;  PIK3CA;  PDGFRA;  GNA12;  RAF1;  PPP1CA;  PTK2;  KRAS;  F2R;  WASL;  
Complement and coagulation cascades BDKRB2;  PROS1;  PLAT;  F7;  A2M;  F3;  FGB;  F10;  F2R;  

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